It should be housed in a 30 gallon or larger aquarium with live sand as the substrate, and an attached populated refugium. The Diamond Goby uses shallow burrows in the substrate as refuge, keeping the substrate well oxygenated. It rarely becomes aggressive towards other fish, but is territorial, and will fight with its own kind unless they are a mated pair.
The Diamond Goby feeds off the bottom as it sifts through the sand. Its diet should include a variety of live and frozen brine shrimp, mysis shrimp, live black worms, and prepared foods for carnivores. It should be fed frequently.